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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support clinical examination, electroencephalography and neuroimaging. Extracellular microRNAs may be potentially ideal biomarkers since some are expressed uniquely within specific brain regions and cell types. Cerebrospinal fluid offers a source of microRNA biomarkers with the advantage of being in close contact with the target tissue and sites of pathology. Here we profiled microRNA levels in cerebrospinal fluid from patients with temporal lobe epilepsy or status epilepticus, and compared findings to matched controls.

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Matchmaking part 19b

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Two different tumor samples with different cytoplasmic staining intensity for FXYD3 weak vs strong. Abstract Approximately half of the colorectal cancer CRC patients develop metastatic disease. The following filter settings were used to search in the data portal: Patients with low expression of miR in their primary tumor had increased median PFS compared to those with high expression of miR Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes.

On the other hand, it is also likely that more factors are involved in the biogenesis and maintenance of miRNA levels. In an attempt to explain the link between miR down-regulation and increased PFS, putative target genes were identified. Questo sito utilizza cookies per migliorare la tua esperienza. Box plots for four exemplary miRNAs displaying differences between the expression in tumor and normal mucosa.

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